(Frankfurt, June 2, 2022) Our antibiotics are currently at risk of losing their potency as antibiotic resistance reaches dangerous levels. Hatice Ceren Ates of the FIT Freiburg Center for Interactive Materials and Bioinspired Technologies and the Department of Microsystems Engineering (IMTEK) has invented a device that will make an important contribution to the fight against antibiotic resistance and has been awarded the €5,000 Klee Prize in recognition of this.
Current medical practice aims to keep the concentration of medication in a patient’s blood within a certain therapeutic range. This is a difficult task, since that range varies widely from person to person. “To make the regular measurements required for this both quick and affordable, I developed an electrochemical multiplex biosensor for temporally monitoring antibiotics. It can work simultaneously with various bodily fluids – such as blood, plasma, urine, saliva or respiratory gas samples,” explains Ates, a 30-year-old doctoral student. “In the study, we show that the sensor can even be used to measure the concentration of antibiotics in the breath of mammals, which can then be correlated with the antibiotics level in their blood. That was not possible until now.”